What Is Testosterone?

During male adolescence, testosterone stimulates the development of muscles, deepens the voice and encourages the growth of the penis and testes. Testosterone is also what regulates muscle mass, bone mass and sex drive during adulthood. Testosterone is produced mainly in the testes but also in the adrenal glands. Most men experience a decline in their testosterone levels after the age of 30 as part of the natural aging process.

What Causes Low Testosterone?

Hypogonadism in males happens when the testicles don’t produce enough testosterone. Hypogonadism may also be known as gonad deficiency. It may be called low serum testosterone or andropause when it happens in males.

Primary hypogonadism

Primary hypogonadism is caused by underactive testes because they don’t manufacture sufficient levels of testosterone for optimal growth and health. This underactivity can be caused by an inherited trait or it can be acquired by an accident or illness.

Inherited conditions include:

  • Undescended testicles: This occurs when the testicles fail to descend from the abdomen before birth
  • Klinefelter’s syndrome: A condition in which a man is born with three sex chromosomes: X, X, and Y.
  • Hemochromatosis: An excess of iron in the blood causes testicular failure or pituitary damage
  • Types of testicle damage:

  • Physical injury to the testicles: Injury must occur to both testicles to affect testosterone levels
  • Mumps orchitis: A mumps infection can injure testicles
  • Cancer treatment: Chemotherapy or radiation can damage testicles
  • Secondary hypogonadism

    Secondary hypogonadism is caused by damage to the pituitary gland or hypothalamus. These parts of the brain control hormone production by the testes.

    Inherited conditions include:

  • Pituitary disorders: These can be caused by drugs, kidney failure, or small tumors
  • Kallmann syndrome: A condition connected to abnormal hypothalamus function
  • Inflammatory diseases: This includes tuberculosis, sarcoidosis, and histiocytosis. These diseases can impact the pituitary gland and the hypothalamus
  • HIV/AIDS: This can affect the pituitary gland, hypothalamus, and testes
  • Acquired circumstances include:

  • Medications: Opioid pain medications and steroids can affect function of the pituitary gland and hypothalamus
  • Normal aging: Aging affects production and response to hormones
  • Obesity: High body fat can affect hormone production and response
  • Concurrent illness: Severe emotional stress or physical stress from an illness or surgery can cause the reproductive system to temporarily shut down
  • Mixed hypogonadism

    Mixed hypogonadism is more common with increased age. People undergoing glucocorticoid therapy can develop the condition. It also can affect people with sickle-cell disease, thalassemia, or alcoholism.

    Are You Suffering From Low Testosterone?

  • Lack of Energy – Have you noticed that you no longer enjoy some of your favorite activities due to lack of energy? Do you feel fatigued regularly?

  • Poor Sleep – Do you toss and turn at constantly during the night? Do you get less than 6 hours of sleep a night on a regular basis?

  • Declining Libido – Have you noticed a change in your sex drive? Is your sex life affecting your relationship with your partner?

  • Decreased Muscle and Strength – Do you feel weaker than you used to? Are you working out but finding it hard to maintain muscle mass?

  • Weak Erections – Do you find yourself unable to perform during intimate moments? Have you been embarrassed by your inability to perform like you once did?

  • Depression – Are you feeling down although your life circumstances are the same as they were when you were happy? Do you feel negative about life in general?

  • Declining Ability to Concentrate – Is it hard for you to remember simple things? Do you find it difficult to focus and perform everyday tasks?
  • Low Testosterone Symptoms

    Low T Physical Symptoms:

  • Decreased sexual desire
  • Weight gain or obesity
  • Lack of energy or fatigue
  • Muscle weakness or softness
  • Sleep problems and insomnia
  • Skin wrinkling; thinning hair
  • Muscle and bone density loss
  • Low T Psychological Symptoms:

  • Lack of sexual function or arousal
  • Depression or deep sadness
  • Nervousness or anxiety
  • Withdrawal from others
  • Feelings of hopelessness
  • Shyness and loss of drive
  • Irritability and mood swings
  • Memory loss and lack of focus
  • Testosterone Replacement Therapy

    Injectable Testosterone

    Injectable testosterone is a popular form of testosterone replacement therapy today. It’s effective, fast acting, and there’s no risk of transference to those around you. Reduce risks associated with other delivery systems such as messy gels and surgical implants. Testosterone replacement therapy is used for patients with low levels of the testosterone. We use it to treat conditions caused by lack of the hormone, such as delayed puberty, impotence, and other hormonal imbalances. Benefits include increased sexual desire, increased muscle mass, increased erectile function, and sperm production.

    Testosterone Boosters-hCG/Chlomiphene

    The male body can become deprived of testosterone with age. Whether it is from eating poorly or exercising less, the body’s hormones and biological processes can become so reduced in number that they are practically ineffective. Luteinizing hormones stimulate testosterone levels and androgen receptors to be more responsive allowing for sexual dysfunctions to be corrected. Luteinizing hormones are often used in combination with anti-estrogens.


    Anti-Estrogens act to either decrease the amount of estrogen in the body or block the estrogen receptors. In men, this causes the natural testosterone levels to increase. Symptoms associated with high estrogen include: water retention, acne, gynecomastia, low sex drive, and irritability. Anti-Estrogens are often used in combination with luteinizing hormones.

    The medical information on this site is provided as an information resource only. It is not intended to diagnose, treat, cure, or prevent any health problem. No action should be taken solely on the contents of this website or our testimonials. Always consult a physician or qualified health professional on any matters regarding your health or on any opinions expressed within this website. Results vary from patient to patient.